The Evidence Files
Long-form articles on peptide safety, clinical research, and how to read past the hype. Updated as the science evolves.
Is BPC-157 Safe? What the Evidence Actually Says
BPC-157 has a compelling safety profile in animal studies. Human trial data is a different story. Here is what the evidence actually shows before you inject anything.
Read article →Peptide Influencers vs. Published Research: A Scorecard
We matched 6 popular peptide influencer claims against what the peer-reviewed literature actually says. The gap is instructive.
Read article →TB-500 for Recovery: Hype or Science?
TB-500 is the most popular peptide in sports recovery circles. The science behind it is more complicated than the marketing suggests — and one clinical trial failed to show the effect everyone promises.
Read article →How to Evaluate Peptide Claims Before You Buy
A practical framework for separating legitimate peptide science from marketing copy. Seven questions to ask before you trust any peptide claim.
Read article →Peptide Side Effects Nobody Talks About
The peptide community discusses benefits constantly. Side effects get buried, minimized, or omitted entirely. Here is what the evidence and users actually report.
Read article →GHK-Cu for Skin: What Does the Research Actually Say?
GHK-Cu is in half the premium skincare products on the market. The research behind it is more interesting — and more limited — than the marketing suggests.
Read article →How Peptide Clinics Actually Work (And What They Won't Tell You)
Peptide clinics have exploded across the US. Here is the business model, what oversight actually exists, and the questions you should be asking before you sign up.
Read article →Semaglutide vs. Peptide Alternatives: What the Evidence Actually Shows
GLP-1 drugs like semaglutide have dominated weight loss headlines. The peptide community is pitching alternatives. Here is how the evidence actually compares.
Read article →Red Flags When Buying Peptides Online
The gray-market peptide supply chain has serious quality control problems. Here are the specific warning signs that tell you a vendor is not one you should trust with compounds you plan to inject.
Read article →The 5 Most Overhyped Peptides of 2026
Five peptides generating enormous hype in biohacking communities with evidence that does not match the claims. An evidence-based reality check.
Read article →BPC-157 vs TB-500: Which Actually Works?
BPC-157 and TB-500 are the two most popular "healing peptides" in biohacking circles. Here is a direct evidence comparison — mechanisms, human data, and where each one actually stands.
Read article →Are Peptide Supplements Worth It? A Cost-Per-Outcome Analysis
Peptide protocols can cost $200–800 per month. Here is an honest cost-per-outcome analysis that prices in the probability that the outcome actually happens.
Read article →Epithalon for Anti-Aging: Evidence Review
Epithalon is claimed to reverse aging by extending telomeres. Here is what the research actually shows — the good data, the gaps, and why the "fountain of youth" framing gets ahead of the evidence.
Read article →Peptide Stacking: What the Research Says About Combining Peptides
Peptide stacking — combining multiple compounds simultaneously — is a staple of biohacker protocols. Here is what the research actually shows about combined use, and the real risks that stacking discussions skip.
Read article →NAD+ Peptides vs IV NAD+: What the Evidence Actually Shows
NAD+ has become the longevity industry's favorite molecule. IV infusions, oral supplements, and NAD+ precursor peptides all claim to restore youthful cellular function. Here is what the evidence supports.
Read article →Sermorelin: The Anti-Aging Peptide That Isn't
Sermorelin is marketed as a "natural" growth hormone releaser that restores youthful GH levels without the downsides of actual HGH. Here is where the claim falls apart.
Read article →Ipamorelin Fat Loss Claims: What the Studies Actually Show
Ipamorelin is called "the gentle giant" of growth hormone secretagogues — selective, clean, and allegedly perfect for cutting fat without cortisol side effects. Here is what the human evidence says.
Read article →CJC-1295: Modified GRF and the Half-Life Hype
CJC-1295 is marketed with extraordinary half-life claims — 2 weeks of elevated GH from one injection, according to peptide clinics. Here is what the pharmacokinetics actually show.
Read article →PT-141: From Failed Tanning Drug to Bedroom Miracle?
Bremelanotide (PT-141) was initially developed as a melanocortin receptor agonist for UV-free tanning. It failed that trial but produced an unexpected side effect: spontaneous erections in male subjects. The modern marketing of PT-141 as a libido treatment follows a winding path.
Read article →AOD-9604: When a Fragment of Growth Hormone Promises Weight Loss
AOD-9604 is a 15-amino-acid fragment of the growth hormone molecule, specifically the portion claimed to mediate fat-mobilizing effects without the growth effects of whole GH. The story of why it was abandoned by its original developers is instructive.
Read article →Want evidence, not vibes?
Subscribe for weekly peptide analysis — claims scored, influencer hype debunked. No protocols. No affiliate links.
Not sure about a specific claim?
Paste any peptide claim into the scorer and get an evidence-based BS score in seconds.
Score a Claim →See what the evidence says about the claims you keep hearing about.